Antibacterial Drugs

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Our clients have been a huge inspiration behind the wide array of Ofloxacin Tablets offered by us. We follow the international standards of quality while testing these products. As per the needs and requirements of our clients, we can also customize the packaging quantities of these products.
Features:

Quick response

Precise composition

Longer shelf life

Zero side effect

High purity

Uses:

This medication is used to treat a variety of bacterial infection

Ofloxacin belongs to a class of drugs called quinolone

It works by stopping the growth of bacteria

This treats only bacterial infection

Specification:

Composition: Ofloxacin

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Description:

Salof-MS has in vitro activity against a broad spectrum of gram-positive and gram-negative aerobic and anaerobic bacteria. Ofloxacin is thought to exert a bactericidal effect on susceptible microorganisms by inhibiting DNA gyrase, an essential enzyme that is a critical catalyst in the duplication, transcription, and repair of bacterial DNA.Ofloxacin has been shown to be active against most strains of the following microorganisms both in vitro and in specific clinical infections.

Gram-positive Aerobes:

Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes.

Gram-negative Aerobes:

Citrobacter diversus, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Proteus mirabilis, Pseudomonas aeruginosa

Other:

Chlamydia trachomatis.Ornidazole is a 5-nitroimidazole derivative with actions similar to Metronidazole and Tinidazole and is used in the treatment of susceptible Protozoal Infections and also in Anaerobic Bacterial Infections.It is effective against Protozoa including Entamoeba histolytica, Giardia lambia and Trichomonas spp and Bacteria such as Bacteriodes spp., Anaerobic cocci, Fusobacterium spp., Clostridum spp., and Gardenerlla vaginalis. It acts by damage of DNA strands or inhibition of their synthesis.Both Ofloxacin and Ornidazole are almost completely absorbed from the small intestine when administered orally both having almost 100% bioavailability. Subsequent plasma concentrations of Ofloxacin are obtained in 1-2 hours after oral administration. Peak plasma concentrations of Ornidazole are obtained within 2 hours of administration.The plasma elimination of Ornidazole is 12 to 15 hours and less than 15% is bound to plasma proteins. It is widely distributed in body tissues and fluids. Ornidazole is metabolised in the liver and is excreted in the urine mainly as metabolites and conjugates and to a lesser extent in the faces.

Indications:

Salof-OZ is indicated for the treatment of a wide variety of infections caused by susceptible gram-positive and gram-negative organisms along with anaerobes and protozoa. Gynaecological infections including prophylaxis in gynaecological surgeries. Surgical prophylaxis and surgical wound infections. Respiratory tract infections like lung abscess, aspiration pneumonia, empyema and bronchiectasis. ENT infections like chronic sinusitis, chronic suppurative otitis media, cholesteatoma and mastoiditis. Orofacial and dental infections.Dermatological infections like cellulitis, breast and other cutaneous abscesses, angrene, diabetic and decubitus ulcers.Intra-abdominal infections and diarrhoeas of mixed bacterial and protozoal origin.

Dosage:

The usual adult dose is one tablet of Salof-OZ twice a day. The doses may be increased in severe infections. The duration of treatment depends upon the type and severity of infection.

Contraindications:

Hypersensitivity to the quinolone group or the nitroimidazole group of compounds and in those patients with a history of blood dyscrasias.

Other Details:

Each 5 ml contain

Ofloxacin 50mg

Ornidazole 125 mg

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