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Approx. Rs 99 / Strip Get Latest Price

Etogen-90  Tablet Each Film Coated Tablet Contains: Etoricoxib   90 mg Etoricoxib is Anti-inflammatory medicines NSAID used to treat rheumatoid, arthritis, Gout and osteoarthritis Indication and Usage: ???Mild to moderate pain for example headaches, muscle aches, arthritis, backache, toothache or the symptoms of a cold. ???Control a fever(high temperature, also known as pyrexia) – for example, when someone has the flu (influenza). ???It is also used for the treatment of Rheumatoid arthritis, Gout and osteoarthritis. Pharmacokinetics: It is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 10 to 60 minutes after oral administration. It is distributed into most body tissues. Plasma protein binding is negligible at usual therapeutic doses but increases with increasing doses. The elimination half-life varies from about 1 to 3 hours. It is metabolised extensively in the liver and excreted in the urine mainly as inactive glucuronide and sulfate conjugates. Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). Mode of Action: Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). This reduces prostaglandins (PGs) generation from arachidonic acid. Side effects: Side effects of Etoricoxib and Paracetamol are most likely to be minor like: ???Constipation ???Swelling of your face, lips, tongue ???Nausea Contraindications: ???Caution when used during pregnancy. ???Contraindicated in lactation. ???Caution in active peptic ulceration, and cerebrovascular disease. Storage: Store in cool and dry place.

Approx. Rs 18 / Strip Get Latest Price

Each Film Coated Tablet Contains:
Etoricoxib 60 mg
Paracetamol 325 mg
Before knowing its combination, we should need to know that how they work individually, so you know that Etoricoxib is Anti-inflammatory medicines NSAID used to treat rheumatoid, arthritis, Gout and osteoarthritis and Paracetamol is also NSAID and it is used to relieve mild to moderate aches and pains associated with conditions such as headaches, migraine, toothache, teething, colds and flu. It is also useful for reducing fever.
It has been demonstrated by recent studies concomitant administration of Etoricoxib and Paracetamol shows better symptoms relief compared with modest improvement of mild to moderate pain, inflammation and fever.

Indication and Usage:
Combination of Etoricoxib and Paracetamol used to treat:
Mild to moderate pain for example headaches, muscle aches, arthritis, backache, toothache or the symptoms of a cold.
Control a fever(high temperature, also known as pyrexia) – for example, when someone has the flu (influenza).
It is also used for the treatment of Rheumatoid arthritis, Gout and osteoarthritis.

Pharmacokinetics:
It is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 10 to 60 minutes after oral administration. It is distributed into most body tissues. Plasma protein binding is negligible at usual therapeutic doses but increases with increasing doses. The elimination half-life varies from about 1 to 3 hours.
It is metabolised extensively in the liver and excreted in the urine mainly as inactive glucuronide and sulfate conjugates. Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2).

Pharmacodynamics:
Paracetamol is a p-aminophenol derivative that exhibits analgesic and antipyretic activity. It does not possess anti-inflammatory activity. Paracetamol is thought to produce analgesia through a central inhibition of prostaglandin synthesis.

Mode of Action:
Paracetamol works as a painkiller by affecting chemicals in the body called prostaglandins. Prostaglandins are substances released in response to illness or injury. Paracetamol blocks the production of prostaglandins, making the body less aware of the pain or injury. Paracetamol reduces temperature by acting on the area of the brain that is responsible for controlling temperature. Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). This reduces prostaglandins (PGs) generation from arachidonic acid.

Drug Interactions:
BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT CHILD HAS NOW OR HAS HAD.
Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications in this combination of etoricoxib and Paracetamol Risk of side effects increased with concomitant use of , ciclosporin.

Side effects:
Side effects of Etoricoxib and Paracetamol are most likely to be minor like:
Constipation
Swelling of your face, lips, tongue
Nausea

Contraindications:
Caution when used during pregnancy.
Contraindicated in lactation.
Caution in active peptic ulceration, and cerebrovascular disease.

Storage:
Store in cool and dry place.
 

Approx. Rs 65 / Strip Get Latest Price

Description:

• We are known as the leading trader, supplier and distributor of Lornoxicam Tablets. These products are packed in customized quantities as per the requirements and needs of clients. These products are tested as per international standards of quality to ensure better quality outputs.

Features:

• Quick response
• Precise composition
• Longer shelf life
• Zero side effects
• High purity
• High effectiveness

Each Tablet Contains:

• Lornoxicam 8 mg

Other details:

• Inflammation and pain are the integral part of surgical/ non surgical trauma and many diseases. Lornoxicam is a non steroidal anti-inflammatory drug with analgesic properties and belongs to the class of oxicams

• Lornoxicam inhibits the prostaglandin synthesis by inhibiting COX-1/COX-2 system. It also inhibits the production of pro-inflammatory cytokines TNF-alpha, IL-1beta, IL-6, and IL-8 and the inducible no synthase. It is safe for longer duration and has less side effects

Indications:

• Pain relief
• Rheumatoid arthritis
• Osteoarthritis
• Low back pain
• Post operative pain management
• Gynecological surgery: Hysterectomy
• General surgery

Absorption:

• Extensively absorbed from the GI tract. Peak plasma concentration within 1-2 hours (oral) or 25 min (IM)

Distribution:

• 99% bound to plasma proteins

Metabolism:

• Metabolised to its inactive metabolite

Excretion:

• Excreted in the faeces (as metabolites) and urine (as unchanged drug). Mean elimination half life of 3-4 hours

Approx. Rs 185 / Strip Get Latest Price

Bromenz-D Tablets
• Trypsin BP 48mg
• Bromelain 90mg
• Rutoside Trihydrate BP 100mg
• Diclofenac 50mg

Overview: BROMENZ-D Tablets contains Trypsin, Bromelain, Rutoside Trihydrate and Diclofenac. It is a synergistic combination of naturally occuring systemic enzymes (Trypsin and Bromelain), phytonutrient (Rutoside Trihydrate), anti-inflammatory and analgesic (Diclofenac). Class: Trypsin and Bromelain belongs to the class of naturally occuring systemic enzymes and Rutoside Trihydrate is a phytonutrient. Diclofenac belongs to the class of non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.

Indications: BROMENZ-D Tablets can be used in the treatment of following conditions:
• Post-operative pain.
• Edema and inflammation in contusions, lacerations, cuts, sinusitis, otitis, externa, PID (Pelvic inflammatory disease), tooth extraction, cellulitis, abscess, sport injuries, sprains and surgery.
• Painful osteoarthritis, rheumatoid arthritis, spondylopathies, tendonitis, polymyositis, dermatomyositis and gout.
• Pain management of kidney stones and gallstones, chronic pain in cancer, post-traumatic pain, dysmenorrhea and acute migraines.
• Temporary relief from aches, pains and muscle soreness due to everyday activity. Dosage: One BROMENZ-D Tablet three times a day or as directed by Physician. Mechanism of Action: Trypsin and Bromelain are proteolytic enzymes. They break peptide bond inside protein molecules. Bromelain exerts anti-inflammatory activity by affecting prostaglandin synthesis. Rutoside is a glycoside and has antioxidant effect. It increases the strength of the walls of the blood capillaries and regulates their permeability. Diclofenac inhibit both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis.

Approx. Rs 80 / Strip Get Latest Price

DEGOUT-40 (febuxostat) tablet for oral use

INDICATIONS AND USAGE

• DEGOUT-40 is a xanthine oxidase (XO) inhibitor indicated for the chronic management of hyperuricemia in patients with gout.
• DEGOUT-40 is not recommended for the treatment of asymptomatic hyperuricemia.

DOSAGE AND ADMINISTRATION

• DEGOUT-40 is recommended at 40 mg or 80 mg once daily. The recommended starting dose of DEGOUT-40 is 40 mg once daily. For patients who do not achieve a serum uric acid (sUA) less than 6 mg per dL after 2 weeks with 40 mg, DEGOUT-40 80 mg is recommended.
• DEGOUT-40 can be administered without regard to food or antacid use.
• No dose adjustment is necessary when administering DEGOUT-40 to patients with mild to moderate renal or hepatic impairment.

DOSAGE FORMS AND STRENGTHS

• Tablet: 40 mg, 80 mg.

CONTRAINDICATIONS

• DEGOUT-40 is contraindicated in patients being treated with azathioprine, mercaptopurine, or theophylline.

WARNINGS AND PRECAUTIONS

• Gout Flare: An increase in gout flares is frequently observed during initiation of anti-hyperuricemic agents, including DEGOUT-40. If a gout flare occurs during treatment, DEGOUT-40 need not be discontinued. Prophylactic therapy (i.e., non-steroidal anti-inflammatory drug (NSAID) or colchicine upon initiation of treatment) may be beneficial for up to six months.
• Cardiovascular Events: A higher rate of cardiovascular thromboembolic events was observed in patients treated with DEGOUT-40 than allopurinol in clinical trials. Monitor for signs and symptoms of MI and stroke.
• Liver Enzyme Elevation: Transaminase elevations have been observed in DEGOUT-40-treated patients. Monitor liver function tests periodically.

ADVERSE REACTIONS

• Adverse reactions occurring in at least 1% of DEGOUT-40-treated patients, and, at least 0.5% greater than placebo, are liver function abnormalities, nausea, arthralgia, and rash.

DRUG INTERACTIONS

• Concomitant administration of DEGOUT-40 with XO substrate drugs, azathioprine, mercaptopurine, or theophylline could increase plasma concentrations of these drugs resulting in severe toxicity.

 USE IN SPECIFIC POPULATIONS

• There is insufficient data in patients with severe renal impairment. No studies have been conducted in patients with severe hepatic impairment. Caution should be exercised in these patients.
• No studies have been conducted in patients with secondary hyperuricemia (including patients being treated for Lesch-Nyhan syndrome or malignant disease, or in organ transplant recipients); therefore, DEGOUT-40 is not recommended for use in these patients.

Approx. Rs 14 / Piece Get Latest Price

We are providing Diclofenac Injections 75mg/ ml