Pharmaceutical Tablets

Approx. Rs 78 / Bottle Get Latest Price

Salvica-of Tablets
Cefixime…… 200 mg….. β lactam antibiotics (Third generation cephalosporin antibiotic)
Ofloxacin IP…200 mg…. Second-generation fluoroquinolone
 
Clinical Pharmacology
Cefixime:
Pharmacokinetic Actions
Cefixime is absorbed after oral administration and has a bioavailability of about 40% to 50%.
Its protein binding is approximately 60% with an average half-life of 3 to 4 hours.
The distribution volume is 3.5 l/kg and total clearance is approximately 15 l/h. The half-life in plasma is 10-1 2 hours and gives a 24 hour effect after dosing once daily. Its excretion is through renal and biliary route.
Ofloxacin:
Pharmacokinetic Actions
It is absorbed after oral administration and has a bioavailability of about 50 to 70%.
Its protein binding is approximately 60% wEth an average half-life of 0.75 to 1 hours.
Its excretion is through renal route.
Mechanism Of Action:
Cefixime: It is bactericidal beta-lactam antibiotic (such as penicillins). Cefixime disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan.
Ofloxacin: Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division. The fluoroquinolones interfere with DNA replication by inhibiting an enzyme complex called DNA gyrase. This can also affect mammalian cell replication.
Recent studies have demonstrated a correlation between mammalian cell cytotoxicity of the quinolones and the induction of micronuclei. As such some fluoroquinolones may cause injury tothe chromosome of eukaryotic cells.

Approx. Rs 270 / Strip Get Latest Price

Cefixime-Clav is indicated for the treatment of:

• Uncomplicated Urinary Tract Infections
• Otitis Media
• Pharyngitis and Tonsillitis
• Acute Bronchitis and Acute Exacerbations of Chronic Bronchitis
• Uncomplicated gonorrhea (cervical/urethral)

We are looking for Pharma PCD & Pharma franchisee queries from all over India. 

"Third party inquiries are also solicited"

Approx. Rs 139 / Strip Get Latest Price

SALOF-OZ PLUS TABS Ofloxacin I.P. 200 mg Ornidazole I.P. 500 mg Lactic Acid Bacillus 120 Million spores. Saccharomyces Boulardii 2 Million spores. INDICATIONS Diarrhea GI Infections Dysentry Abdominal pain Traveler's diarrhea Lactose Intolerance Ofloxacin Offers broad spectrum of activity against gastrointestinal pathogens including Escherichia Coil and species of Salmonella, Shigella, Campylobacter Yersinia, Plesiomonas, Aeromonas and vibrio. A total cure achieved in 96.5% of cases with diarrhoea and in 100% of cases with dysentery. Ornidazole Combination of ofloxacin with ornidazole significantly reduces number of watery stool and associated symptoms like nausea,abdominal pain. Shows tolerability rate of 98.43%. Lactic Acid Bacillus Helps in normalising intestinal flora elicits positive results in treating acute infections diarrhoea. Alleviates bacterial/viral induced diarrhoea espically in infants. Saccharomyces Boulardii Significantly reduces the duration of diarrhea from -26.05 to -13.34,stool frequency -1.38 to -0.10 after intervention compared with control. Inhibits neutralizes bacterial virulence factors.

Approx. Rs 180 / Strip Get Latest Price

Mypod 100/200mg Tablets

Cefpodoxime - A third generation cephalosporin .

Cefpodoxime proxetil is used orally for the treatment of mild to moderate respiratory tract infections (i.e., acute exacerbations of chronic bronchitis, acute maxillary sinusitis, community-acquired pneumonia) caused by susceptible bacteria; the treatment of acute otitis media caused by susceptible bacteria; and the treatment of pharyngitis and tonsillitis caused by Streptococcus pyogenes (group A β-hemolytic streptococci). The drug also is used orally for the treatment of uncomplicated gonorrhea and for the treatment of mild to moderate uncomplicated skin and skin structure or uncomplicated urinary tract infections caused by susceptible bacteria.

Prior to initiation of cefpodoxime proxetil therapy, appropriate specimens should be obtained for identification of the causative organism and in vitro susceptibility tests. Cefpodoxime proxetil may be started pending results of susceptibility tests but should be discontinued if the organism is found to be resistant to the drug.

 

Acute Otitis Media

Pharyngitis and Tonsillitis

Respiratory Tract InfectionsAcute Exacerbations of Chronic Bronchitis

Acute Sinusitis

Community-acquired Pneumonia

Skin and Skin Structure Infections

Urinary Tract Infections

Gonorrhea and Associated InfectionsUncomplicated Gonorrhea

Disseminated Gonococcal Infections

 

Approx. Rs 12 / Strip Get Latest Price

Garispas-DS Tab

Each tablet contains:

Composition:

Dicyclomine ....................................................................20 mg

Mefenamic acid............................................................500 mg

Indication:

Adjunct in gastrointestinal disorders characterised by smooth muscle spasm. As urinary antispasmodic, renal colics, spasmodic dysmenorrhoea.

Description:

Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic).

 

Dosage : As per the physician’s advice.

Approx. Rs 52 / Strip Get Latest Price

Description

• disclaimer the information given below is for the use of medical sales rep and is not for doctors. Information given below is inadequate for treating a patient

garitel-40 tablet

composition

telmisartan ip 40 mg

telmisartan is a newer type of blood pressure medicine known as an angiotensin ii receptor blocker (arb for short). As the name implies, telmisartan blocks angiotensin ii receptors. This decreases the effectiveness of a chemical known as angiotensin ii, which normally causes blood vessels to narrow (constrict). By blocking the effects of angiotensin ii, telmisartan causes blood vessels to relax.

indications and usage

high blood pressure (hypertension)

 

drug interaction

Complementry mechanism of action

Reduction in peripheral resistence with arb

Reduction of fluid volume with diuretics

Arbs counteract reactive increase in blood pressure related to diuretic induced renin secretion

Arbs ameliorates diuretic induced potassium depletion

Well tolerated; fewer metabolic disturbances

No significant variation in pharmacokinetic parameters of telmisartan in presence of hydrochloroth.iazide

 

combination of telmisartan with hydrochlorot.hiazide was found to be more effective than each agent alone in lowering blood pressure. Indeed , combining telmisartan with hydrochlorothia.zide enhances the antihypertensive efficacy of telmisartan in patients not adequately controlled with telmisartan alone.

 

pharmacokinetic

telmisartan is orally well absorbed and metabolized to an active metabolite which is more potent than losartan as at1 antagonist. Orally administered hydrochlor.othiazide is rapidly absorbed and diuretic effect is seen in 1 hour and their duration lasts up to 12-24 hours. Both telmisartan and hydroc.hlorothiazide has longer duration of actions. These agents are bound to plasma proteins to varying degrees and this has no correlation to their half-life.

 

 

pharmacodynamics

the pharmacodynamics of telmisartan & hydrochlo.rothiazide has been investigated in vitro and in vivo in rodents, guinea pigs, rabbits and dogs. The combination of telmisartan with hydroc.hlorothiazide (40 mg/12. 5 mg and 80 mg/12. 5 mg) is expected to benefit patients with hypertension who are not adequately responsive to telmisartan alone.

 

contraindications

Second and third trimesters of pregnancy.

Biliary obstructive disorders.

Severe hepatic impairment.

storage

this medicinal product does not require any special temperature storage conditions. Store in the original package in order to protect from moisture.

Approx. Rs 57 / Strip Get Latest Price

We are making our name in offering the nation with a series of affordable and innovative medicines for a healthier living, for all. We are here presenting a range of Pharma PCD, Pharma Franchise, Pharmaceutical Capsules, Pharmaceutical Tablets, Soft Gel Capsules, Pharmaceutical Syrups, Dry Syrups, Pharmaceutical Injections and Pharmaceutical Drops.

As an integrated healthcare solutions provider, we cater to several therapeutic areas. We have also established a cordial relations with reliable vendors from whom we procure the range. Moreover, our agents, Pharma Franchise, Pharma PCD ensure that these are processed using quality ingredients and advanced manufacturing techniques. Our pharmaceutical products are quality tested on different parameters to ensure these are in compliance with the WHO-GMP standards. All our medicines are highly effective and do not have any side effects.

We are looking for Pharma PCD & Pharma franchisee queries from all over India.

"Third party inquiries are also solicited"

Approx. Rs 95 / Strip Get Latest Price

FENASAL-SR

Each Hard Gelatin Capsule Contains:

Aceclofenac IP (As Sustained Release) 200 mg

Rabeprazole Sodium IP (As Enteric Coated) 20 mg

Aceclofenac & Rabeprazole Capsule

We are marketing combination of Aceclofenac and Rabeprazole and we know that Aceclofenac belongs to the group of anti-inflammatory drugs used for the treatment of inflammatory and painful such as low back pain, toothache and joint pain, osteoarthritis and rheumatoid arthritis.

 

Rabeprazole Sodium is an antiulcer drug in the class of proton pump inhibitors. Proton pump inhibitors act by irreversibly blocking the hydrogen/potassium adenosine triphosphatase enzyme system (the H+/K+ ATPase, or more commonly, the gastric proton pump) of the gastric parietal cells. The proton pump is the terminal stage in gastric acid secretion, being directly responsible for secreting H+ ions into the gastric lumen, making it an ideal target for inhibiting acid secretion.

 

Indication and Usage:

● Treatment of duodenal ulcers

● Gastroesophageal reflux disease (GERD)

● Maintaining healing and reducing relapse rates of heartburn symptoms in patients with GERD

● Peptic ulcer disease (PUD)

● Treatment of pathological hypersecretory conditions (Zollinger-Ellison syndrome)

Mechanism of Action:

Combination of Aceclofenac and Rab eprazole is very effective against mild to moderate pain and ulcers. Like other NSAIDS, it has anti-inflammatory and analgesic activity and work by inhibiting the action of synthesis through the inhibition of both COX-1 and COX-2. This leads to the reduction of inflammation, pain, fever, and swelling, which are mediated by prostaglandins.

 

Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+, K+ATPase at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion.

 

Drug Interactions:

BEFORE TAKING THIS TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT PATIENT HAS NOW OR HAS HAD.

Usually drug interactions occur when it is taken with another drug or with food. Before you take a medication for a particular ailment, you should inform the health expert about intake of any other medications including non-prescription medications. Aceclofenac and Rabeprazole may increase plasma concentrations of lithium, digoxin and methotrexate, increase the activity of anticoagulant, inhibits the activity of diuretics, enhance cyclosporin nephrotoxicity and precipitate convulsions when co-administered with quinolone antibiotics. And also decreases the concentration of ketoconazole in the plasma (in 33%), increases the concentration of digoxin (in 22%), and does not interact with liquid antacids.

 

Adverse Effects:

Headache, abdominal pain, dry mouth, dizziness, nausea and diarrhea.

 

Conclusion:

We are marketing Combination of Aceclofenac and rabeprazole which is superior form other NSAIDs as it has selectivity for cox-2, a beneficial cox inhibitor, well tolerated, better GI tolerability and improved cardiovascular safety when compared to other selective cox-2 inhibitors with combination of rabeprazole it work as gastric proton-pump inhibitor. It also work against Gastroesophageal reflux disease by blocking the final step of gastric acid secretion by inhibiting the gastric H+, K+ATPase at the secretory surface of the gastric parietal cell.

Approx. Rs 165 / Unit Get Latest Price

Cefixime 200 with Lactobacillus 60 Million Spores
We Salveo Lifecare, are one of the prominent suppliers of a wide range of Pharmaceutical Drugs. Our wide range includes Capsule, Soft gels, Tablets, SACHET, Injections, dry Syrups, ayurvedic preparations and Syrups.

Approx. Rs 42 / Strip Get Latest Price

We are making our name in offering the nation with a series of affordable and innovative medicines for a healthier living, for all. We are here presenting a range of Pharma PCD, Pharma Franchise, Pharmaceutical Capsules, Pharmaceutical Tablets, Soft Gel Capsules, Pharmaceutical Syrups, Dry Syrups, Pharmaceutical Injections and Pharmaceutical Drops.

As an integrated healthcare solutions provider, we cater to several therapeutic areas. We have also established a cordial relations with reliable vendors from whom we procure the range. Moreover, our agents, Pharma Franchise, Pharma PCD ensure that these are processed using quality ingredients and advanced manufacturing techniques. Our pharmaceutical products are quality tested on different parameters to ensure these are in compliance with the WHO-GMP standards. All our medicines are highly effective and do not have any side effects.

We are looking for Pharma PCD & Pharma franchisee queries from all over India.

"Third party inquiries are also solicited"

Approx. Rs 86 / Strip Get Latest Price

Olmifab-H Tablets

Olmesartan       20 mg

Hydrochlorthiazide 12.5 mg

 

Uses
Olmesartan is used to treat high blood pressure (hypertension), prevention and treatment of heart attack (Myocardial Infarction) and heart failure; when heart is unable to pump sufficient blood. It is also used in patients of diabetes with kidney failure.

Hydrochlorothiazide is used to treat high blood pressure (hypertension). It also treats fluid retention (edema) due to congestive heart failure or cirrhosis of liver or kidney disorder.

How it works

Olmesartan belongs to a class of medications called angiotensin II receptor inhibitors. Angiotensin II is a chemical that causes muscles surrounding the blood vessels to contract, thereby narrowing the blood vessels. Olmesartan is an angiotensin II receptor blocker (ARB) resulting in relaxation of blood vessels, and thus, reduces blood pressure.

 

Hydrochlorothiazide belongs to class of medications called thiazide diuretics. It acts by eliminating the fluid and salts from the body. It works on the kidneys to produce more urine which removes extra water and certain salts from the body which in turn lowers blood pressure and swelling.

Olmesartan and Hydrochlorthiazide when given together, help to lower blood pressure more than if either of them were given alone.

Dose
The recommended starting dose of Olmifab-H is 20/12.5 mg once daily in patients whose blood pressure is not adequately controlled with HCT monotherapy or who experience dose-limiting adverse reactions with hydrochlorothiazide. Dose can be titrated up to 40 /25 mg if necessary.   Indications

Hypertension not controlled with Olmesartan alone.

  Contra Indications Anuria, severe renal and hepatic failure, hypersensitivity, refractory hypokalaemia and hyponatraemia, hypercalaemia and symptomatic hyperuricaemia. Sulphonamide allergy. Pregnancy and lactation

Approx. Rs 150 / Strip Get Latest Price

We are also involved in providing our clients with a wide range of Methylcobalamin 750 Mg with Pregabalin 150 mg that is quite popular in the industry. These products are tested by our team of skilled and trained professionals as per the international standards of quality. We can also customize the packed quantities of these products as per the needs and demands of our clients.

 

Features:

• Quick response

• Precise composition

• Longer shelf life

• Zero side effects

• High purity

• High effectiveness

Indications:

• Possess anxiolytic, analgesic and anticonvulsant activity

• Possess high bioavailability (90%) compared to gabapentin (33-66%)

• Highly effective in relieving the neuropathic pain

• Act as neuroprotective, promotes myelination in neurons

• Peripheral Neuropathy

• Diabetic Neuropathy

• Drug-Induced Neuropathy

• Bell's Palsy

Information provided on this website is of a general nature and is not intended to take the place of a physician's advice. It is vital that persons diagnosed with, or suspected of having, any disease consult with their physician to assure proper evaluation, treatment, and interpretation of information contained on this site

Approx. Rs 248 / Strip Get Latest Price

Each Film Coated Tablet Contains:

Composition:
Cefixime Trihydrate IP
Eq. to Anhydrous Cefixime 200 mg
Azithromycin IP 250 mg
Cefixime Trihydrate is an orally active antibiotic with similar antibacterial spectrum and resistance to β-lactamase as third-generation cephalosporins. It inhibits an enzyme transpeptidase which is responsible for bacterial cell walls synthesis.
 
Azithromycin (AZT) is macrolide antibiotics, it is [9-de-oxy-9a-aza-9a-methyl-9a-homoerythromycin A dihydrate] is an Azalide. It inhibits protein synthesis by the binding 50S ribosomal subunit of the bacteria.
 
Indications:
Cefixime Trihydrate:
Lower Respiratory Tract Infections
Pharyngitis and tonsillitis
Acute sinusitis
Gonorrhea and associated infections
Acute Urinary Tract Infections
Acute Otitis Media
Helicobacter pylori infection
Lyme disease
Salmonella and Shigella infections.
Azithromycin:
Otitis media
Respiratory tract infection
Cystic fibrosis
Anti-inflammatory in COPD Patient
In P. Falciparum Malaria with other Antimalarial drugs
Typhoid fever
Neisseria gonorrhea.
The rationale of Combination:
 
Product Description:
 
A new combination of cefixime and azithromycin with Lactobacillus is used for the treatment of upper and lower respiratory tract infection. Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases may be susceptible to cefixime. Whereas Azithromycin due to its long half-life, which enables once-daily dosing and shorter administration durations, is a property distinct from other macrolides.
Azithromycin:
 
Mechanism of Action:
 
Like all beta-lactam antibiotics, cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.
On the other hand, like other macrolide antibiotics, azithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of the bacterial 70S ribosome. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the process of translation. Its effects may be bacteriostatic or bactericidal depending on the organism and the drug concentration.
 
Adverse Effects:
 
Diarrhea that is watery or bloody.
Chest pain, uneven heartbeats.
Nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin.

Contraindications:
 
Known hypersensitivity to cefixime or other cephalosporins. Contraindicated in patients with a history of liver disease, kidney disease and also muscle disease.
The information given here is not for diagnostic or treatment purpose.

Approx. Rs 90 / Strip Get Latest Price

Our team of skilled and trained professionals has enabled us to provide a wide range of 50 mg Pregabalin Capsules. These products are tested as per the international standards of quality before it is dispatched to the clients. We also have a special team to customize the packed quantities of these products as per the requirements and specifications of our clients.

 

Features:

• Quick response

• Precise composition

• Longer shelf life

• Zero side effects

• High purity

• High effectiveness

 

Other details:

• Pregabalin is a novel, centrally acting neuromodulating agent that was approved by the US Food and Drug Administration (FDA) in 2004 for the treatment of painful diabetic peripheral neuropathy and postherpetic neuralgia

• In 2005 it was approved as adjunctive therapy in adults with partial seizures and recently it has been approved for the treatment of fibromyalgia

• Pregabalin is approved by the European Medicines Agency (EMEA) for the treatment of peripheral and central neuropathic pain in adults, as adjunctive therapy in adults with partial seizures, and for the treatment of generalized anxiety disorder (GAD) in adults

Approx. Rs 8 / Strip Get Latest Price

We have the capability to meet and exceed the expectations with the help of our state of the art facility. Moreover, our ranges are highly effective and offered at best prices.

We are looking for pharma pcd & pharma franchisee enquiries from himanchal pradesh, andra pradesh, jharkhand, bihar, jammu & kashmir, haryana, rajasthan, delhi, uttarakhand, uttar pradesh, west bengal, sikkim, gujrat, maharashtra, tamilnadu, kerala & lakshadeep, chennai, punjab, madhya pradesh, chhattisgarh, orrissa, goa, karnataka.

Approx. Rs 168 / Strip Get Latest Price

Salvica-OZ Tablets

Each Tablets contains

Cefixime         200 mg

Ornidazole       500 mg

SALVICA-OZ Tablets contains Cefixime and Ornidazole.

It is highly stable in the presence of beta-lactamase enzymes. The antibacterial effect of Cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall. Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis.

ORNIDAZOLE contains an imidazole ring which bears a nitro group. It is an anti-amoebic agent. Ornidazole has a broad spectrum -cidal activity against Protozoa and some anaerobic bacteria.

Cefixime is an antibiotic, third-generation cephalosporin. Ornidazole belongs to the class of nitroimidazoles.

SALVICA-OZ Tablets are used in the treatment of the following conditions:

• Diarrhea and dysentery
• Abdominal infections
• Dental infections
• Post-surgical infections
• Infections of female reproductive tract

 

Salvica-OZ (Cefixime Trihydrate 200mg+ Ornidazole 500mg Tablets)

Dosage- 1-2 SALVICA-OZ Tablets once daily or in two divided doses.

Mode of Action-

Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.

Ornidazole has selective toxicity to anaerobic microbes, the mechanism steps involves: Drug enters the cell by diffusion; nitro group of drug is reduced by redox proteins present only in anaerobic organisms to reactive nitro radical which exerts cytotoxic action by damaging DNA and other critical biomolecules; DNA helix destabilization and strand breakage has been observed.

Approx. Rs 123 / Number Get Latest Price

disclaimer: the information given below is for the use of medical sales rep and is not for doctors. information given below is inadequate for treating a patient

fenasal-t4/t8 tab

each film coated tablet contains:

aceclofenac ip 100 mg

thiocholchicoside 4/8 mg

aceclofenac is an orally administered phenylacetic acid derivative with effects on a variety of inflammatory mediators. It is from the class of non-steroidal anti-inflammatory drug (nsaid), related to diclofenac. Through its analgesic and anti-inflammatory properties, aceclofenac provides symptomatic relief in a variety of painful conditions.

thiocolchicoside, a semi-synthetic derivative of the naturally occurring compound colchicoside with a relaxant effect on skeletal muscle, has been found to displace both [3h]gamma-amino butyric acid ([3h]gaba) and [3h]strychnine binding, suggesting an interaction with both gaba and strychnine-sensitive glycine receptors.

indications:
anti-inflammatory, analgesic, neck and shoulder pain .

rationale of combination:

product description:
thiocolchicoside, a semi-synthetic derivative of the naturally occurring compound colchicoside and is a muscle relaxant agent with anti-inflammatory and analgesic actions, also is used topically for the treatment of muscular spasms and for rheumatologic, orthopedic, and traumatologic disorders and has been found to displace both [3h] gamma-amino butyric acid ([3h] gaba) and [3h] strychnine binding, suggesting an interaction with both gaba and strychnine-sensitive glycine receptors. Aceclofenac belongs to a group of medicines called non-steroidal anti-inflammatory drugs (nsaids) and of phenyl acetic acid derivative with effects on a variety of inflammatory mediators. It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause pain, swelling and inflammation. Combination of proven nsaid aceclofenac with an effective non sedating muscle relaxant thiocolchicoside to treat painful muscle spasm.

Approx. Rs 25 / Strip Get Latest Price

Depisal-a tablet

Each tablet contains

Atenolol 50 mg

Amlodipine 5 mg

Atenolol is a cardioselective beta blocker.
Amlodipine is a dihydropyridine calcium channel blocker that blocks the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle.

Pharmacokinetics

Combination of the two drugs results in additive antihypertensive action.

Absorption:

Amlodipine: Plasma levels peak 6-12 hr after oral admin; absolute bioavailability is estimated to be 64-90%.

Atenolol:

Absorption is rapid and consistent but incomplete; about 50% of an oral dose is absorbed in the GI tract; plasma levels peak 2-4 hr after oral admin.

Distribution:

Amlodipine: 93% bound to plasma proteins.

Atenolol: 6-16% bound to plasma proteins.

Metabolism:

Amlodipine: About 90% converted to inactive metabolites hepatically.

Atenolol: Little or no hepatic metabolism.

Excretion:

Amlodipine: 10% of parent compound and 60% of the metabolites are removed in the urine; elimination from the plasma is biphasic with terminal half-life of about 30-50 hr. Atenolol: 50% of the oral dose is removed unchanged in the faeces; absorbed drug is removed mainly via renal elimination; half-life is about 6-7 hr.

 

Atenolol + Amlodipine Indications / Atenolol + Amlodipine Uses

Antihypertensive activity

Atenolol + Amlodipine Adverse Reactions / Atenolol + Amlodipine Side Effects

Headache, hypotension, dizziness, breathlessness, fatigue, muscle cramps, bradycardia, palpitations, flushing, oedema, dyspnoea, dyspepsia, cold extremities. Drowsiness, chestpain impotence rarely. Hypersensitivity reactions.

Precautions

Overdosage may cause hypotension and less commonly, congestive cardiac failure. Unabsorbed drug may be removed by gastric lavage or use of activated charcoal. Symptomatic treatment may be administered.

 

Special Precautions

Excessive fall of BP may occur in elderly patients. Caution in patients with COPD, thyrotoxicosis, congestive failure, vasospastic angina, hepatic renal impairment. Caution in diabetic patients as beta-blockers may mask tachycardia occurring with hypoglycaemia. Withdrawal should be gradual. Lactation. Safety and efficacy have not been established in children. Not to be used in untreated phaeochromocytoma.

 

 

Other Drug Interactions

Additive effect when used with catecholamine depleting drugs; monitor for hypotension and/or marked bradycardia. If used with clonidine, clonidine withdrawal should occur a few days after withdrawal of the beta-blocker to prevent rebound hypertension; if replacing clonidine by beta-blocker, beta-blocker should be introduced only after clonidine administration has stopped for several days. Concurrent use with prostaglandin synthase inhibiting drugs (e.g. indomethacin) may reduce the hypotensive effects of beta-blockers.

 

Dosage

Oral
Chronic stable angina, Hypertension

Adult: Per tablet contains atenolol 25 or 50 mg and amlodipine (as besylate) 5 mg: 1 tab once daily, may increase to 2 tablets daily if needed. 

Elderly: Per tablet contains atenolol 25 mg and amlodipine (besylate) 5 mg: Initiate with 1 tablet daily. 

Renal impairment: Per tablet contains atenolol 25 mg and amlodipine (besylate) 5 mg: Initiate with 1 tablet daily.

Approx. Rs 238 / Strip Get Latest Price

Each Film Coated Tablet Contains:

Composition:

• Cefixime Trihydrate IP
• Eq. to Anhydrous Cefixime :200 mg
• Azithromycin IP  : 250 mg

Cefixime Trihydrate is an orally active antibiotic with similar antibacterial spectrum and resistance to β-lactamase as third generation cephalosporins. It inhibits an enzyme transpeptidase which is responsible for bacterial cell walls synthesis.

Azithromycin (AZT) is macrolide antibiotics, it is [9-de-oxy-9a-aza-9a-methyl-9a-homoerythromycin A dihydrate] is an Azalide. It inhibits protein synthesis by binding 50S ribosomal subunit of the bacteria.

Indications:

Cefixime Trihydrate:

•   Lower Respiratory Tract Infections
•   Pharyngitis and tonsilitis
•   Acute sinusitis
•   Gnorrhea and associated infections
•   Acute Urinary Tract Infections
•   Acute Otitis Media
•   Helicobacter pylori infection
•   Lyme disease
•   Salmonlella and shigella infections.

Azithromycin:

•   Otitis media
•   Respiratory tract infection
•   Cystic fibrosis
•   Anti-inflammatory in COPD Patient
•   In P. Falciparum Malaria with other Antimalarial drugs
•   Typhoid fever
•   Neissaria gonorrhoeae.

Rationale of Combination:

Product Description:

A new combination of cefixime and azithromycin with Lactobacillus is used for the treatment of upper and lower respiratory tract infection. Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. Whereas Azithromycin due to it's long half life, which enables once daily dosing and shorter administration durations, is a property distinct from other macrolides.

Pharmacology:

Cefixime Trihydrate:

Absorption: About 40% to 50% is absorbed. C maxfollowing 200 and 400 mg doses of oral suspension are 3 and 4.6 mcg/mL, respectively. T max occurs between 2 and 6 h following administration of 400 mg and between 2 and 5 h after a 200 mg dose.

Distribution: Protein binding is about 65%.
Elimination About 50% of absorbed dose is excreted unchanged in the urine in 24 h. Serum t ½averages 3 to 4 h, but may be as long as 9 h in some healthy subjects.


Azithromycin:

Absorption: Following oral administration, azithromycin is rapidly absorbed and widely distributed throughout the body. Bioavailability is 37% following oral administration. Absorption is not affected by food.

Distribution: Azithromycin is extensively distributed in tissues with tissue concentrations reaching up to 50 times greater than plasma concentrations. Drug becomes concentrated within macrophages and polymorphonucleocytes giving it good activity against Chlamydia trachomatis.

Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. Please see your health care professional for more information about your specific medical condition and the use of the above mentioned drug

Approx. Rs 140 / Strip Get Latest Price

Salvica-of Tablets Cefixime…… 200 mg….. β lactam antibiotics (Third generation cephalosporin antibiotic) Ofloxacin IP…200 mg…. Second-generation fluoroquinolone   Clinical Pharmacology Cefixime: Pharmacokinetic Actions Cefixime is absorbed after oral administration and has a bioavailability of about 40% to 50%. Its protein binding is approximately 60% with an average half-life of 3 to 4 hours. The distribution volume is 3.5 l/kg and total clearance is approximately 15 l/h. The half-life in plasma is 10-1 2 hours and gives a 24 hour effect after dosing once daily. Its excretion is through renal and biliary route. Ofloxacin: Pharmacokinetic Actions It is absorbed after oral administration and has a bioavailability of about 50 to 70%. Its protein binding is approximately 60% wEth an average half-life of 0.75 to 1 hours. Its excretion is through renal route. Mechanism Of Action: Cefixime: It is bactericidal beta-lactam antibiotic (such as penicillins). Cefixime disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Ofloxacin: Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division. The fluoroquinolones interfere with DNA replication by inhibiting an enzyme complex called DNA gyrase. This can also affect mammalian cell replication. Gram-positive Organisms. •  Streptococcus Pneumoniae, •  Streptococcus Pyo Genes. • Gram-negative Organisms. •  Haemophilus Influenzae •  (beta-lactamase Positive And Negative Strains), •  Moraxefia (branhamefia) Catanhalis (most Of Which Are Beta­lactamase Positive),  Escherichia Coli,  Proteus Mirabilis, Neisseria Gonorrhoeae (including Penicillinase And Non­peniainase Producing Strains).  Cefixime Has Been Shown To Be Active In Vitro Against Most Strains Of The Following Organisms; However, Clinical Efficacy Has Not Been Established. Packing: Strip of  10 tablets Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. Please see your health care professional for more information about your specific medical condition and the use of the above mentioned drug

Approx. Rs 147.5 / Piece Get Latest Price

Our huge team of skilled and trained professionals have enabled us to provide a huge gamut of Co - Amoxiclav 1.2 g Injection. We always test these products for quality to keep up with the industrial standards.These products are packed in varied quantities as per the requirements and demands of the clients. 

Features:
•Quick response
•Precise composition
•Longer shelf life
•Zero side effects
•High purity  
Indications:
•Upper respiratory tract, such as sinusitis, otitis media, tonsillitis
•Lower respiratory tract, such as bronchitis pneumonia
•Urinary tract infections, such as cystitis, urethritis, pyelonephritis
•Skin and soft tissues   Contra-Indications:
•Allergy to penicillins and cephalosporins
•Safety in pregnancy has not been established
•Leoklav is contra-indicated in patients with a previous history of Leoklav associated jaundice/hepatic dysfunction
•Safety and efficacy in children has not been established with the parenteral forms of Leoklav
:
•Quick response
•Precise composition
•Longer shelf life
•Zero side effects
•High purity  
Indications:
•Upper respiratory tract, such as sinusitis, otitis media, tonsillitis
•Lower respiratory tract, such as bronchitis pneumonia
•Urinary tract infections, such as cystitis, urethritis, pyelonephritis
•Skin and soft tissues   Contra-Indications:
•Allergy to penicillins and cephalosporins
•Safety in pregnancy has not been established
•Leoklav is contra-indicated in patients with a previous history of Leoklav associated jaundice/hepatic dysfunction
•Safety and efficacy in children has not been established with the parenteral forms of Leoklav

Approx. Rs 1,358 / Unit Get Latest Price

Cilaric Inj 1g

Imipenem and Cilastatin Injection

Generic Name: imipenem and cilastatin sodium
Dosage Form: injection, powder, for solution

To reduce the development of drug-resistant bacteria and maintain the effectiveness of imipenem and cilastatin for injection (I.V.) and other antibacterial drugs, imipenem and cilastatin for injection (I.V.) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

For Intravenous Injection Only

 

Approx. Rs 82 / Pack Get Latest Price

Description:

• We are also the leading trader and supplier of a huge range of Levofloxacin Tablets 500 Mg. These products are offered to our clients in varied packaging quantities as per their needs and guidelines. Tested in accordance to the international standards of quality, these products are very pure and have a long life span.

Features:

• Quick response
• Precise composition
• Longer shelf life
• Zero side effects
• High purity
• High effectiveness

Specification:

• Composition: Levofloxacin

Uses:

• Treatment to Prevent Anthrax following Exposure to Disease
• Acute Inflammation of the Maxillary Sinus
• Acute Maxillary Sinus S. Pneumoniae Bacteria Infection
• Acute Maxillary Sinus H. Influenzae Bacteria Infection
• Acute Maxillary Sinus M. Catarrhalis Bacteria Infection
• Pneumonia caused by Pneumococcus Bacteria
• Bacterial Pneumonia caused by Haemophilus Influenzae, Pneumonia due to the Bacteria Haemophilus Parainfluenzae, Bacterial Pneumonia caused by Strep
• Bacterial Pneumonia caused by Staphylococcus
• Pneumonia due to Methicillin-Sensitive

Information provided at this web site is of a general nature and is not intended to take the place of a physician's advice. It is vital that persons diagnosed with, or suspected of having, any disease consult with their physician to assure proper evaluation, treatment and interpretation of information contained on this site.

Approx. Rs 62 / Strip Get Latest Price

We are highly appreciated by the clients for manufacturing and supplying Cardio Diabetic Drugs. Moreover, the plates offered by us are tested on various parameters so as to ensure their high purity. Tested as per the international standards of quality, these products are in high demand in the market.
Features:

Quick response

Precise composition

Longer shelf life

Zero side effects

High purity

High effectiveness

Uses:

Glykad 62 Tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Specification:

Composition: Metformin 1000 mg, Glimipride 2 mg.

Information provided at this web site is of a general nature and is not intended to take the place of a physician's advice. It is vital that persons diagnosed with, or suspected of having, any disease consult with their physician to assure proper evaluation, treatment and interpretation of information contained on this site.

Approx. Rs 65 / Strip Get Latest Price

Metformin SR 500 mg,
Pioglitazone 15 mg
Glimepiride 2 mg

J Indian Med Assoc. 2005 Aug;103(8):447-50.Evaluation of efficacy and safety of fixed dose combination of glimepiride 2 mg pluspioglitazone 15 mg plus metformin SR 500 mg in the management of patients with type-2 diabetes mellitus.Meshram DM1, Langade DG, Kinagi SB, Naikwadi AA, Morye V, Chopra D AbstractAn estimated 25 million Indians currently have diabetes and the projections indicate Indians would be the largest group by the year 2025 AD. An open, phase III, multicentric study was conducted to determine the efficacy and tolerability of the triple drug combination glimepiride 2 mg plus pioglitazone hydrochloride 15 mg plus metformin SR 500 mg for 8 weeks in 101 Indian patients with type 2 diabetes mellitus. The study revealed that the triple drug combination could achieve the recommended goals, recommended by American Diabetic Association, for fasting blood glucose < or = 140 mg/dl and glycosylated haemoglobin (HbA1c) of < or = 8%. After 8 weeks, the mean fasting blood glucose (baseline 189.61) was reduced to 111.68 (41% reduction); the mean glycosylated haemoglobin (baseline 10.32) was significantly reduced to 7.54 (26% reduction). The triple drug combination significantly reduced the levels of triglyceride, low density lipoproteins and total cholesterol. These significant levels were achieved within 8 weeks and all patients tolerated the drug well with no reported case of serious adverse events including hypoglycaemia. There were also no reported drug interactions in the study. Since the decrease in HbA1c was continuous and throughout the study, a further decrease in the HbA1c levels would have been noted since the present trial was designed for a period of 8 weeks. Thus, the present study confirms the efficacy and safety of FDC of the triple drug combination in patients with type 2 diabetes.

Approx. Rs 52 / Strip Get Latest Price

We are into a business of Pharma Franchise,Pharma PCD range of Pharma Medicines that are incompliance with the WHO-GMP standards & safe toconsume & give the aid from suffering from variousdiseases.

We are making our name in offering the nation with a series of affordable and innovative medicines for a healthier living, for all. We are here presenting a range of Pharma PCD, Pharma Franchise, Pharmaceutical Capsules, Pharmaceutical Tablets, Soft Gel Capsules, Pharmaceutical Syrups, Dry Syrups, Pharmaceutical Injections and Pharmaceutical Drops.

As an integrated healthcare solutions provider, we cater to several therapeutic areas. We have also established a cordial relations with reliable vendors from whom we procure the range. Moreover, our agents, Pharma Franchise, Pharma PCD ensure that these are processed using quality ingredients and advanced manufacturing techniques. Our pharmaceutical products are quality tested on different parameters to ensure these are in compliance with the WHO-GMP standards. All our medicines are highly effective and do not have any side effects.

We are looking for Pharma PCD & Pharma franchisee queries from all over India.

"Third party inquiries are also solicited"

Approx. Rs 65 / Strip Get Latest Price

Telmisartan And Amlodipine (Oral Route) Descriptions

Telmisartan and amlodipine is a combination of medicines that may be used alone or with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.

Telmisartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, the blood vessels relax and this decreases blood pressure. When blood pressure is lowered, the amount of blood and oxygen that go to the heart is increased.

Amlodipine is a calcium channel blocker (CCB). It affects the movement of calcium into the cells of the heart and blood vessels. As a result, amlodipine relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

· Tablet