Gastro Products -Anti ulcerants, Pre-Pro Biotics, Liver Tonics

Approx. Rs 145 / Strip Get Latest Price

Each Hard Gelatin Capsule Contains:Composition:Rabeprazole Sodium (EC pellets) 20 mg Levosulpiride (SR pellets) 75 mg
Indications:Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD).Maintenance of Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD)Healing of Duodenal UlcersTreatment of Pathological Hypersecretory Conditions, Including Zollinger-Ellison Syndrome.Irritable bowel syndromeChronic Gastritis.
Mechanism of Action:Rabeprazole belongs to a class of anti secretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.Levosulpiride is more selective and acts primarily as a dopamine D2 antagonist. The prokinetic effect of Levosulpiride is mediated through the blockade of enteric (neuronal and muscular) inhibitory dopamine D2 receptors. Results also show that levosulpiride also acts as a moderate agonist at the 5-HT receptor. The serotonergic (5-HT4) component of Levosulpiride may enhance its therapeutic efficacy in gastrointestinal disorders. This property, together with antagonism at D2 receptors, may contribute to its gastrointestinal prokinetic effect.

Pharmacology:Pharmacodynamics:Rabeprazole prevents the production of acid in the stomach. It reduces symptoms and prevents injury to the esophagus or stomach in patients with gastroesophageal reflux disease (GERD) or ulcers. Rabeprazole is also useful in conditions that produce too much stomach acid such as Zollinger-Ellison syndrome.Levosulpiride acts as prokinetic agent.
Pharmacokinetics:
Rabeprazole:Absorption: Absolute bioavailability is approximately 52%.Route of Elimination:Following a single 20 mg oral dose of 14C-labeled rabeprazole, Approximately 90% of the drug was eliminated in the urine, primarily as thioether carboxylic acid; itslucuronide, and mercapturic acid metabolites.
Levosulpiride:Absorption: Oral bioavailability is about 30%; peak plasma concentrations after about 3hr.Route of Elimination:Mainly via urine. Plasma half-life: 9.7 hr (oral); 4.3 hr (IV).
Side Effects:Headache, dizziness, diarrhoea, constipation, stomach pain, muscle weakness.
DISCLAIMER=Information provided at this web site is of a general nature and is not intended to take the place of a physician's advice. It is vital that persons diagnosed with, or suspected of having, any disease consult with their physician to assure proper evaluation, treatment and interpretation of information contained on this site.

Approx. Rs 80 / Piece Get Latest Price

Esogen-40 Inj
Esomeprazole for Injection 40 Mg (Lyophilised Injection)

Description:
Esomeprazole is the S-Isomer of Omeprazole and Reduces Gastric Acid Secretion Through a Specific Targeted Mechanism of Action. It is a Specific Inhibitor of the Acid Pump in the Parietal Cell. Both the R- and S-Isomer of Omeprazole Have Similar Pharmacodynamic Activity.

Mechanism of Action:
Esomeprazole is a Weak Base and is Concentrated and Converted to the Active Form in the Highly Acidic Environment of the Secretory Canaliculi of the Parietal Cell, Where It Inhibits the Enzyme H+k+-Atpase C the Acid Pump and Inhibits Both Basal and Stimulated Acid Secretion.

Indications:
Short-Term (4-8 Weeks) Treatment of Erosive Esophagitis; Maintaining Symptom Resolution and Healing of Erosive Esophagitis; Treatment of Symptomatic Gastroesophageal Reflux Disease; As Part of a Multidrug Regimen for Helicobacter Pylori Eradication in Patients With Duodenal Ulcer Disease (Active Or History of Within the Past 5 Years); Prevention of Gastric Ulcers Associated With Continuous Nsaid Therapy.

Dosage and Administration:
The Recommended Adult Dose of Esomeprazole I.v is Either 20 Or 40 Mg Given Once Daily by Intravenous Injection (No Less Than 3 Minutes) Or Intravenous Infusion (10 to 30 Minutes). Esomeprazole I.v. Should Not Be Administered Concomitantly With Any Other Medications Through the Same Intravenous Site and Or Tubing. the Intravenous Line Should Always Be Flushed With Either 0.9% Sodium Chloride Injection, Usp, Lactated Ringer Injection, Usp Or 5% Dextrose Injection, Usp Both Prior to and After Administration of Esomeprazole I.v. for Injection.

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Approx. Rs 52 / Bottle Get Latest Price

LOMORID SUSPENSION

EACH 5 ML CONTAINS

Racecadotril IP 15 mg

 

 Racecadotril is an anti diarrheal drug which acts as a peripherally acting enkephalinase inhibitor and help to reduces the secretion of water and electrolytes into the intestine. Infections of the gastro intestinal tract, especially infectious diarrhea, are among the most common debilitating infectious diseases, afflicting people of all ages around the world. Diarrhea can be defined as the passage of loose or watery stools, usually at least three times in a 24 hr period it may be accompanied by anorexia, nausea vomiting, abdominal cramps. It is not a disease but sign of some infections or gastro intestinal disorders.

 

Indication and Usage:

??? It is used for the treatment of the acute and chronic diarrhea.

??? Acute diarrhea usually lasts for a few days and is typically caused by an infection of some sort caused by bacteria, viruses or parasites.

??? Chronic diarrhea persists longer than does acute diarrhea, generally longer than four weeks. Chronic diarrhea can indicate a serious disorder, such as ulcerative colitis or Crohn's disease.

 

Mechanism of Action:

Racecadotril increases the availability of endogenous (enkephalins) by inhibiting the membrane-bound enkephalinase. These enkephalins activate δ- receptors in the GI tract. This leads to a reduction in cAMP mucosal levels, resulting in a reducted secretion of water and electrolytes in the intestinal lumen.

 

Common Bacteria, Viruses, and Parasites that Cause Diarrhea:

 

Bacteria:

E. coli : E. coli are harmless and live in the intestines of healthy humans and animals. E. coli produces a powerful toxin that can cause a severe infection.

Salmonella :Salmonella is a bacteria that infects the intestines and causes diarrhea, fever, and abdominal cramps 12 to 72 hours after infection.

 

Viruses:

Rotavirus:Rotavirus is the most common cause of severe diarrhea among children. The disease is characterized by vomiting and watery diarrhea for three to eight days, and fever and abdominal pain occur frequently.

Giardia : Giardia lamblia has become recognized as one of the most common waterborne diseases in humans in the United States. Giardia is a tiny parasite that lives in the intestines of people and animals.

 

Pharmacokinetics:  

Absorption: Racecadotril is quickly absorbed orally. The inhibiting activity of the plasmatic encephalinase appears in 30 minute. The amplitude and the duration of action of the racecadotril are related to the administered dose. The peak concentration is of 2.5 hrs approximately and corresponds to an inhibition of 90% of the enzymatic activity for the administered dose of 1.5 mg/kg. The duration of inhibiting activity on the plasma encephalinase is of approximately 3 hours. The half life is 3-4 hours.

Distribution: The tissue distribution is weak; it accounts for only approximately 1% of the administered dose. The racecadotril is fixed at 90% on plasma proteins (mainly albumin). The bioavailability of Racecadotril is not modified by food, but the peak of activity is delayed for 1.5 hours approximately. Duration of 4 hours action close. It does not cross the hemato-encephalic barrier.

Metabolism: Racecadotril is a prodrug, which is rapidly absorbed after by oral income and hydrolyzed to thiorphan as active metabolites.

 

Side Effects:

• Vomiting

• Nausea

• Constipation

• Abdominal pain

 

Contraindications:

It is contra-indicated in the event of intolerance with fructose, malabsorption of glucose and galactose or of invert sugar-isomaltase deficit. It is contra-indicated in patients with known Hypersensitivity.

 

Approx. Rs 45 / Strip Get Latest Price

OMESAL-D CAPSULES

Omesal-D Capsules – A Combination of Omeprazole 20mg & Domperidone 10 mg 

Salveo Lifecare offers Omesal-D capsules which contain a combination of Omeprazole 20mg. & Domperidone 10mg ingredients. This combination of medicine is mainly effective in treating the ulcer, indigestion, and stomach acid production.

In this combination, Omeprazole ingredient helps to cure severe heartburn, GERD (Gastroesophageal Reflux Disease) and other stomach related disorders caused due to excessive acid production in the stomach. It is also useful in the healing of a damaged food pipe due to too much stomach acid (erosive esophagitis).

Domperidone is a kind of peristaltic stimulant which helps in preventing nausea & vomiting caused by certain medications, indigestion, or some diseases. It is a digestive system movement booster and also beneficial in certain stomach related disorders such as heavy bloating, stomach fullness, belching, gas, and heartburn.

We at Salveo Lifecare recommend you to avoid the excess dosage of Omesal-D capsules and store these capsules as directed by your medical doctor or physician.

Approx. Rs 16 / Unit Get Latest Price

Pre-Pro Biotic Sachet EACH SACHETS OF 1 GM CONTAIN Lactobacillus Acidophilus …0.50 billion Lactobacillus Rhamnosus...0.50 billion Bifidobacterium Bifidum ..........0.50 billion Bifidobacterium Longum........0.50 billion Streptococcus Thermophillus....0.25 billion Saccharomyces Boulardii.........0.25 billion Fructo Oligosaccharide.............200 mg L-Glutamine...............................100 mg Fungal Amylase..........................50 mg

Approx. Rs 298 / Strip Get Latest Price

UDISAL-300 TAB

UrsoDeoxycholic  Acid Tablet

Composition:

Each Film Coated Tablet Contains:

Urso Deoxycholic Acid BP             300 mg

Packing Available:5 x 10 Alu Alu

 

Ursodeoxycholic Acid is a naturally occurring bile acid. It is used for the treatment of some liver conditions. This may include diseases such as biliary Artesia (blockage of the bile duct) and cholestasis of cystic fibrosis (occurs when bile flow is restricted). It is also used in the treatment of gallstones.

Indications:

It is a biliary composition and flow-altering drug occurring naturally in mammals, and is sometimes known as a bile acid.

It is used to reduce the cholesterol content of biliary fluid (produced by the liver and stored in the gall bladder for secretion into the intestine to digest fats).

In general this drug is used to dissolve gallstones made of cholesterol and to treat a condition called primary biliary cirrhosis (in which the bile ducts are damaged, causing bile to accumulate in the liver, which is then damaged itself).

Benefits of being on this drug in patients with primary biliary cirrhosis include the prevention or treatment of lack of bile flow from the liver to the intestine (cholestasis), and the dissolving of gallstones in patients who have this problem.

Usage:

Treatment of primary biliary cirrhosis

Dissolving gallstones that are radiolucent (they do not show up on X-rays) that are in patients with a functioning gallbladder.

Mechanism of Action:

Ursodeoxycholic acid (UDCA) is used in the treatment of cholestatic liver diseases, gallstone dissolution, and for patients with hepatitis C virus infection to ameliorate elevated alanine aminotransferase levels. The efficacy of UDCA treatment has been debated and the mechanisms of action in humans have still not defined. Suggested mechanisms include the improvement of bile acid transport and/or detoxification, cytoprotection, and anti-apoptotic effects.

Pharmacology:

Ursodeoxycholic acid 1 is the 7[beta]-hydroxy epimer of chenodeoxycholic acid and is normally present in only trace amounts in the bile. Oral administration of pharmacological doses markedly decreases biliary cholesterol saturation.

Complete or partial dissolution of radiolucent gallstones located in a functioning gallbladder occurred in about 40 to 55% of patients treated with ursodeoxycholic acid in controlled studies of 6 months duration.

Pharmacokinetics:

Ursodeoxycholic acid suppresses hepatic synthesis and secretion of cholesterol and also inhibits intestinal absorption of cholesterol.

Absorption: Rapidly and completely absorbed from the GI tract.

Excretion: Faeces.

 

Side Effects:

Feeling sick (nausea), Vomiting, Diarrhea, Gallstone calcification (calcium deposits form in the gallstone),Itching.

Contraindications:

Ursodeoxycholic acid should be used with caution in: women who are likely to become pregnant or who are breastfeeding. It should not be used in: women who are pregnant, patients with a gall bladder that is not working properly, or who have gallstones which contain calcium (i.e. are opaque on an X-ray), have severe liver problems, stomach ulcers or inflammation of the bowel.

Storage:

Store at room temperature, 15-30° C (59-86°F). Keep away from moisture. 

Disclamour:  the information given above is educational and is not for the purpose of diagnosis or treatment. Pls consult a medical practitioner. This drug should be take only on the advice of a medical practitioner

Approx. Rs 57 / Strip Get Latest Price

Each Tablet of PANAV-D contains: Pantoprazole … 40 mg Domperidone … 10 mg PANAV-D is primarily advocated for managing symptom of burning in various acid peptic disorders associated with nausea and / or vomiting. It is indicated for GERD, reflux esophagitis, nonulcer dyspepsia, gastroparesis and idiopathic hiccup, or any other acid-peptic disease accompanied by nausea and / or vomiting like acute gastritis including that induced by nonsteroidal anti-inflammatory drugs (NSAIDs). Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. Please see your health care professional for more information about your specific medical condition and the use of the above mentioned drug

Approx. Rs 145 / Strip Get Latest Price

Features

• Hepasyl Softgel capsule
• Silymarine 140 mg;
• Alpha Lipoic Acid 50 mg,
• L-Ornithine, L-Aspartate 150 mg,
• Selenium 50 mcg


We're identified as one of the reputed corporations of this industry, engaged in distributing and supplying a vast variety of Silymarin and L-Ornithine L-Aspartate Softgel Capsule from Mohali, Punjab, India. Hepasyl Cap is a combination of Silymarin and L-Ornithine L- Aspartate with the added benefits of Alpha Lipoic acid and Selenpmethionine to improve liver health and function. Hepasyl Cap can be used as an adjunct to drugs which are hepatotoxic. Hepasyl Cap treats fatty liver, liver damage and cirrhosis of the liver and effectively helps alleviation of symptoms in these patients when combined with primary therapy.Presented in a strip of 10, one to two Hepasyl Cap capsules can be taken daily just before breakfast. Customers can acquire it from us at very reasonable price.

Approx. Rs 55 / Bottle Get Latest Price

Backed by our several years of experience in this domain, we have emerged as a reputed firm offering a wide range of Antiflatulent Antacid Suspension. Our team of skilled and qualified professionals have the expertise to pack these products in varied quantities as per the requirements and needs of our clients. These products are also tested as per the international standards of quality by a special team of testers.

Features:

• Quick response
• Precise composition
• Longer shelf life
• Zero side effects
• High purity
• High effectiveness

Uses:

• Hyper Acidity
• Heart Burn
• Peptic Ulcers
• Dyspepsia
• Flatulence
• Reflux
• Oesophagitis

Specification:

• Composition: Magaldrate anhydrous 400 mg, simethicone 20 mg.

Approx. Rs 98 / Strip Get Latest Price

Pre-Probiotic , Pro-Probiotic ..........In Drug

Fructo-oligosaccharide............. 200 mg
Glutamine ..................................... 100 mg
Bifidobacterium Bifidium .......... 150 Billion
Bifidobacterium Longum .......... 150 Billion
Lactobacillus Acidophilus... ….. 300 Billion
Streptococcus Thermophilus ... 150 Billion

Charomyces boulardii- is a yeast strain which helps to keep the digestive tract clear and is beneficial to sufferers of diarrhoea and Crohn's disease. It is a friendly beneficial yeast that fights fungal/yeast infections such as Candida: it is much used in France, where they refer to it as the yeast- fighting yeast. L-Glutamine - As said above supports immune function, repairs and heals the gut wall and is a source of fuel for white blood cells.

Probiotics work by:

• Supporting immune Function.
  Aiding the digestive system.
  Enhancing the body's absorption of food and nutrients.
  Repopulating depleted intestinal flora.
  Protecting the gut wall against harmful bacteria that can cause 'leaky gut'. A leaky gut allows pathogens to break through the gut wall causing havoc in the body.
  Keeping your gut clean.
  Supporting vitamin production.
  Supports the destroying of toxins and carcinogens.

Approx. Rs 130 / Bottle Get Latest Price

Description:

• With from commitment towards quality, we are engaged in supply and trade of Lecithin And Silymarin Suspensions. Moreover, the products offered by us are checked on predetermined parameters so as to ensure their adherence with set industry standards and norms. Our team of skilled and trained professionals are also capable to provide these products in a customized quantities as per the requirements and needs of our clients.

Specification:

• Composition: Each 5 ml contains: Silymarine 35 mg, Lecithin 125 mg.

The Functions of the Liver:

• Efficient liver function is extremely important to the overall health of a person and this depends on constant supplies of antioxidant nutrients. If the liver isn't working efficiently and antioxidant defenses are low, the effects can be seen in any cell, tissue or organ in the body. A vast constellation of symptoms can result from impaired liver function that at first glance may seem to have nothing at all to do with the liver.
  The liver has a number of important functions, some of the main ones being:
  Detoxification of potentially toxic chemicals from both inside and outside of the body including drugs, alcohol and toxins from intestinal microbes. Accomplished with antioxidant nutrients and enzymes such as glutathione.
  Storage of sugar as 'glycogen' and regulation of blood sugar levels.
  Production and storage of proteins as well as the regulation of many substances involved in protein metabolism.
  Production of bile which aids in the digestion of fats.
  Production of blood proteins, clotting factors and substances important to the production of red blood cells (erythrocytes)
  Regulation of a number of hormones.
  Neutralization of 'free-radicals' by antioxidants. Free radicals are highly reactive oxygen molecules that can damage tissues.
  Storage of vitamins, mainly A, D and B12
  As you can see the liver is involved in a wide array of metabolic activities and it requires a large amount of energy and nutrients to accomplish these effectively.

Silymarine

• The milk thistle plant contains silymarine and related flavonoids which are some of the most potent liver-protecting substances known. These flavonoids are powerful antioxidants so protect the liver from damaging toxins and free radicals. They also stimulate healing and the production of new liver cells and cause the liver to increase production of glutathione, the bodies most important antioxidant and detoxifying substance. Silymarin has been proven to both protect liver cells and repair existing damage in animals intoxicated with mushroom toxins, medicines, heavy metals or toxic organic solvents. Human studies have also shown decreased mortality in patients with alcoholic liver damage who are treated with silymarin.

• Lecithin is sold over-the-counter in the USA as a health food supplement.

• Lecithin consists of fatty acids and the nutrient choline. Cirrhosis, a Liver disorder is a life-threatening condition, which the liver becomes filled with fibrous tissue, and as the result functions poorly. The researchers showed that lecithin may act by increasing the liver's breakdown of the fibrous tissue that causes cirrhosis. Lecithin aids in the absorption of thiamin by the liver and is needed to help repair the damage to the liver caused by alcoholism. Other studies also have confirmed the protective effect of lecithin in proper functioning of the liver.

Approx. Rs 78 / Strip Get Latest Price

Description:

• We are the proud supplier and trader of a wide variety of Pantoprazole And Domperidone Sustained Release Capsules. Following the global standards of quality, these products are checked thoroughly before being dispatched to the clients. We also customize the packaging quantities of these products as per the requirement and guidelines of our esteemed clients.

Features:

• Quick response
• Precise composition
• Longer shelf life
• Zero side effects
• High purity
• High effectiveness

Specification:

• Composition: Pantoprazole & Domperidone

Uses:

Pantoprazole

• Pantoprazole is used to heal and prevent gastrointestinal (stomach and bowel) problems related to excess acid.
• It is a proton pump inhibitor (PPI), sometimes known as an ulcer healing drug.
• Pantoprazole is used to reduce gastric acid secretion from the stomach and treat a number of acid-related gastrointestinal conditions.
• It is used to heal intestinal and stomach ulcers and to treat and manage gastro-oesophageal reflux disease (GORD, a condition in which acid rises up from the stomach into the oesophagus [gullet] with symptoms of heartburn, acid regurgitation and pain on swallowing).

Domperidone

• Domperidone is used to help to move food faster through your food pipe (oesophagus), stomach and gut.
• This is so that it does not stay in the same place for too long.
• It also helps stop food flowing the wrong way back up your food pipe.
• It is a dopamine agonist, and belongs to a group of medicines known as anti-emetics.
• It is used to help your digestive system move food contents through it normally and in the right direction.

Approx. Rs 78 / Strip Get Latest Price

CAP. ESOGEN-DSR• Each Hard Gelatin Capsule Contains:Esomeprazole Magnesium Eq. to Esomeprazole (As enteric coated pellets) 40 mg Domperidone (10 mg of immediate release pellets and 20 mg of Sustained release pellets) 30 mg
Esmoprazole is a proton pump inhibitor administered orally as the magnesium salt in treatment of gastroesophageal reflux disease and in the treatment of duodenal ulcer associated with Helicobacter pylori infection.Domperidone belongs to propulsives. It is used to treat ulcers and acid stomach.
Indications and Usage: Acid peptic disease – both active disease treatment and for maintenance therapy. Gastroesophageal reflux disease and erosive esophagitis. Hypersecretory states like Z.E. syndrome etc.
Mechanism of Actions: Domperidone is a peripheral dopamine D2-receptor antagonist, which regulates the motility of gastric and small intestinal smooth muscle. It increases the duration of antral and duodenal contractions and also LES resting pressure, thus stimulating gastric emptying and is also effective in relief of symptoms of reflux esophagitis. Antiemetic activity is due to the blockade of dopamine receptors in the chemoreceptor trigger zone. Esmoprazole inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of H+/K+ ATPase of the gastric parietal cell. It is activated at an acidic pH to a sulphenamide derivative that binds irreversibly to H+/K+ ATPase, an enzyme system found at the secretory surface of parietal cells. It thereby inhibits the final transport of hydrogen ions (via exchange with K ions) into the gastric lumen.

Pharmacology:Domperidone blocks the action of dopamine. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which, among others, regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa). Esmoprazole is a Proton pump inhibitors which block acid at the final common pathway of secretion-that is, at the proton pump-regardless of the stimulus of acid secretion, and thereby offer by far the most potent suppression of gastric acid.

Side Effects:Headache, Nausea, Vomiting, Dizziness, Vertigo, Reversible confusion, Agitation, Depression and hallucinations.

DISCLAIMER=Information provided at this web site is of a general nature and is not intended to take the place of a physician's advice. It is vital that persons diagnosed with, or suspected of having, any disease consult with their physician to assure proper evaluation, treatment and interpretation of information contained on this site.

Approx. Rs 64 / Strip Get Latest Price

Description:

• The state of the art technology and advanced skills of our qualified professionals have enabled us to provide our esteemed clients with a wide range of Rabeprazole & Domperidone Capsules. Tested as per the international standards of quality, we have ensured that these products do not falter at the time of functioning. We can also customize packaging quantities of these products to meet the specifications of the clients.

Features:

• Quick response
• Precise composition
• Longer shelf life
• Zero side effects
• High purity
• High effectiveness

Specification:

• Composition: Rapebrazole & Domperidone

Uses:

Rapebrazole

• Rabeprazole is used to treat and maintain healing of gastroesophageal reflux disease (GERD).
• It is also used to treat symptoms, such as heartburn and regurgitation, of non-erosive reflux disease (NERD).

Domperidone

• Domperidone is used to help to move food faster through your food pipe (oesophagus), stomach and gut.
• This is so that it does not stay in the same place for too long.
• It also helps stop food flowing the wrong way back up your food pipe.
• It is a dopamine agonist, and belongs to a group of medicines known as anti-emetics.
• It is used to help your digestive system move food contents through it normally and in the right direction.

Approx. Rs 19.5 / Tablet Get Latest Price

Gulworm-I Tablets Composition: Albendazole IP             400 mg Ivermectin IP   6 mg  Before knowing its combination , first we should need to know how they work individually and we know that Ivermectin is a broad-spectrum antiparasitic medicine and effective against worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, filariasis, enterobiasis and Albendazole is used as a drug indicated for the treatment of a variety of worm infestations. It is a broad spectrum anthelmintic, effective against roundworms, tapeworms, and flukes of humans.  It has been demonstrated by recent studies concomitant administration of Ivermectin and Albendazole suspension, shows better symptoms relief compared with modest improvement of onchocerciasis some worm infestations like ascariasis, trichuriasis, filariasis. It is also effective against Flatworms, Flukes, Fasciolosis, Tapeworm, Cysticercosis, Echinococcosis and Hook worms. Indication and Usage: It is traditionally used against worms. It is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, filariasis, enterobiasis, and some epidermal parasitic skin diseases, including scabies. It is effective against Flatworms, Flukes, Fasciolosis, Tapeworm, Cysticercosis, Echinococcosis, Nematodes, Enterobiasis, Trichuriasis Ascariasis and Hookworm. Mechanism of Action: We are using combination of Ivermectin and Albendazole suspension and from mode of action we come to know that how it effective in our body so Ivermectin kills the larval Onchocerca volvulus worms microfilariae that live in the subcutaneous tissue of an infected person. It is believed to paralyse or kill the microfilariae gradually, so avoiding the intense inflammatory responses induced when they die naturally. Treatment with ivermectin relieves intense skin itching and halts the progression towards blindness. Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies. Side Effects: Abdominal pain Dizziness Headache Nausea Vomiting

Approx. Rs 43 / Unit Get Latest Price

Pantoprazole Sodium for Injection 40 mg (Lyophilised Injection)

PANAV-40 INJ for Injection is supplied as a freeze-dried powder in a clear glass vial fitted with a rubber stopper and crimp seal containing Pantoprazole sodium, equivalent to 40 mg of pantoprazole.

Mechanism Of Action:
Pantoprazole is a Proton Pump Inhibitor (PPI) that suppresses the final step in gastric acid production by covalently binding to the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The binding to the (H+, K+)-ATPase results in a duration of antisecretory effect that persists longer than 24 hours for all doses tested. 

INDICATIONS:
PANAV-40 INJ is indicated for the treatment of gastric ulcer, duodenal ulcer, moderate and severe reflux oesophagitis. 


Dosage: 
PANAV-40 INJ is recommended only in cases where the oral administration is not indicated. The recommended dose is intravenous administration of the content of one vial ( 40 mg Pantoprazole ) once daily for 7 days. 

Duodenal Ulcer:
Duodenal Ulcers generally heal within 2 weeks. If a 2-week period of treatment is not sufficient, healing will be achieved in almost all cases within a further 2 weeks. 

Gastric Ulcer Gastro-oesophageal reflux: A 4 week period is usually required for the treatment of gastric ulcers gastro-oesophageal reflux. If this is not sufficient, healing will usually be achieved within a further 4 weeks. 

Elderly: No dose adjustment is necessary in the elders.

Patients with Impaired Renal Function: No dose adjustment is necessary in patients with impaired renal function. 

Patients with Impaired Hepatic Function: In patients with severe liver impairments, the daily dose should be reduced to 20 mg Pantoprazole. Also, in these patients the liver enzymes should be monitored during PANAV-40 INJ therapy. In case of liver enzymes, it should be discontinued. 

Direction For Reconstitution:
The content of the vial needs to be reconstituted with 10 ml of Sodium Chloride Injection BP 0.9% w/v before injection.

This freshly prepared solution should be administered intravenously over 2 to 15 minutes, either as a slow injection or it may be further diluted with 100 ml of Sodium Chloride Injection BP 0.9 % w/v or 5% Glucose Injection and administered as a short term infusion.

The duration of administration should be 2 to 15 minutes. The reconstituted solution must be used within 12 hours of preparation. 

Adverse Effects:
Treatments with Pantoprazole can occasionally lead to headache or diarrhea. Rarely nausea/vomiting, abdominal pain, flatulence, constipation, allergic reactions such as skin rash and pruritus may occur. Individual cases of oedema, blurred vision, fever, dizziness, thrombophlebitis, depression or myalgia subsiding after termination of therapy have been reported. 

Presentation: PANAV-40 INJ is available as Box of one 10 ml vial with 10 ml Sodium Chloride Injection BP as diluent. 

Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. Please see your health care professional for more information about your specific medical condition and the use of the above mentioned drug.

Approx. Rs 139 / Strip Get Latest Price

SALOF-OZ PLUS TABS Ofloxacin I.P.                                            200 mg Ornidazole I.P.                                         500 mg Lactic Acid Bacillus                                120 Million spores. Saccharomyces Boulardii                  2 Million spores.   INDICATIONS Diarrhea GI Infections Dysentry Abdominal pain Traveler's diarrhea Lactose Intolerance   Ofloxacin Offers broad spectrum of activity against gastrointestinal pathogens  including Escherichia Coil and species of Salmonella, Shigella, Campylobacter Yersinia, Plesiomonas, Aeromonas and vibrio. A total cure achieved in 96.5% of cases with diarrhoea and in 100% of cases with dysentery. Ornidazole Combination of ofloxacin with ornidazole significantly reduces number of watery stool and associated symptoms like nausea,abdominal pain. Shows tolerability rate of 98.43%. Lactic Acid Bacillus Helps in normalising intestinal flora elicits positive results in treating acute infections diarrhoea. Alleviates bacterial/viral induced diarrhoea espically in infants. Saccharomyces Boulardii Significantly reduces the duration of diarrhea from -26.05 to -13.34,stool frequency -1.38 to -0.10 after intervention compared with control. Inhibits neutralizes bacterial virulence factors.

Approx. Rs 22 / 200 ml Bottle Get Latest Price

Approx. Rs 98 / Strip Get Latest Price

PRE-PRO BIOTIC CAPSULE